Hepatology research has focused on developing traditional therapies as pharmacological medicines to treat liver diseases and cirrhosis. Thus The present study was designed to evaluate the hepatoprotective activity of ethanolic extract of Pancratium Longiflorum leaves and flowering stem against thioacetamide (400mg, SC) induced hepatic damage in albino rats was observed. The ethanolic extract at dose of (300mg and 600mg/kg, p.o) Offered significant (p<0.001) hepatoprotective action by reducing the serum marker enzymes like SGPT, SGOT, ALP. They also reduced the elevated level of total bilirubin and reduction in pentobarbitone induced sleeping time, preventing induced reduction in ascorbic acid excretion in rat urine, increased bromsulphalein (BSP) uptake and histopathological studies further confirm the hepatoprotective activity of Pancratium Longiflorum. When compared to the thioacedamide treated control groups the results obtained were compared with Silymarin (100mg, p.o.) the standard drug.
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